METABOLIC SYNDROME: A GLOBAL HEALTH PROBLEM.

Metabolic syndrome: a global health problem.

It is well known, and recognised by the WHO, that the prevalence of obesity and overweight has increased substantially in a short period of time and is now considered a global pandemic. It is also a preventable risk factor for many other diseases such as type 2 diabetes, hypertension and hypercholesterolaemia (all associated with cardiovascular problems), tissue inflammation and even cancer.

Technically, obesity is caused by a chronic positive imbalance between energy intake and expenditure, resulting in storage of excess energy in the form of fat in adipose tissue. The problem is that obesity has an impact not only on the health of the individual, but it is estimated that in the USA it also affects medical costs by approximately $2741 per person per year according to some studies.

These pathologies associated with obesity have led in recent years to the emergence of the term metabolic syndrome (MetS) as one of the most widely used concepts in the field of health sciences.

Metabolic syndrome comprises several risk factors such as obesity, hypertension, hypercholesterolemia and type 2 diabetes, together with a genetic predisposition and a sedentary lifestyle. In the United States, a frequency of 21-33% has been reported, which has led to a high emphasis on diagnosis and treatment.

In this respect, it is necessary to design ingredients that have a positive impact on the individual's metabolic health along with a healthy lifestyle.

Metabolaid: The role of AMPK in the regulation of cellular energy metabolism.

AMPK is a crucial enzyme in the regulation of cellular energy metabolism. It plays an important role in the pathophysiology of diseases such as metabolic syndrome and type 2 diabetes.

For this reason, AMPK has become a major therapeutic target that has been extensively studied by science and for which several studies have been reported on active ingredients capable of modulating its function for the treatment of these pathologies.

Activation of this enzyme triggers regulatory processes in various organs affected by metabolic syndrome such as the liver, skeletal muscle, heart, adipose tissue and hypothalamus.

This enzyme is activated by physical exercise but can be activated by certain active compounds such as anthocyanins from hibiscus and verbascoside from lemon verbena extract, which act synergistically, helping people with metabolic syndrome characteristics to control their weight and cardiovascular health. The botanical extracts hibiscus and lemon verbena are able to activate this enzyme thus Metabolaid, a patented botanical ingredient based on hibiscus and lemon verbena extracts. These two extracts have been formulated to act synergistically, increasing the effects of the individual extracts by more than 6 times.

Metabolaid®

• Acts as a fat burner by activating AMPK.
• Reduces blood pressure.
• Reduces cholesterol and triglyceride levels.
• Helps regulate satiety.
• Improves the diversity of the intestinal microbiota.

Metabolaid® is the result of more than 12 years of peer-reviewed scientific studies in both animal models and clinical studies. The extraction process used to obtain it is completely natural. Metabolaid® is supplied in powder form and is easy to formulate into ready-to-drink tablets, capsules and supplements.

A tailor-made solution with clinically proven ingredients to achieve and maintain a healthy weight.

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